Hubungan durasi ketuban pecah dini dengan asfiksia neonatorum di RSUD Negara tahun 2020

I Gde Ketut Fendy Indrapermana; Vidya Saraswati Putri Duarsa; Iswara Somadina Duarsa

doi:10.15562/ism.v12i1.981

Hubungan durasi ketuban pecah dini dengan asfiksia neonatorum di RSUD Negara tahun 2020

I Gde Ketut Fendy Indrapermana ,

Vidya Saraswati Putri Duarsa ,

Iswara Somadina Duarsa ,

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DOI: https://doi.org/10.15562/ism.v12i1.981 |
Published: 2021-04-01

Abstract

Introduction: Premature rupture of membranes (PROM) was still a significant cause of maternal or neonatal morbidity. Prolonged PROM caused asphyxia due to oligohydramnios that exert pressure to the placenta and causing vasoconstriction of blood vessels. This study aimed to understand the association between duration of PROM and the presence of asphyxia among neonates delivered in RSUD Negara in 2020.

Methods: This was a cross-sectional study involving woman who was diagnosed with PROM and delivered in RSUD Negara during January - December 2020, included by total sampling. The duration of PROM, neonatal asphyxia, parity, maternal age and mode of delivery data were collected from medical records. The data were analyzed by the Chi-square test. The p-value <0.05 was considered significant.

Results: This study included 220 mothers with PROM. The incidence of asphyxia neonatorum in this study was 17.7%. The majority of the patients were 20-35 years old (75.5%), had parity <2 or> 3 (79.1%), had assisted-delivery (63.6%) and duration of PROM was 6-12 hours (59.5%). The duration of PROM was significantly associated with the incidence of neonatal asphyxia (p<0.05).

Conclusion: The longer duration of PROM was associated with a higher incidence of neonatal asphyxia. Effective management of PROM is important to minimize the risk of neonatal asphyxia.

Latar belakang: Ketuban pecah dini (KPD) masih menjadi penyebab morbiditas maternal maupun neonatus. KPD berkepanjangan berpotensi menyebabkan asfiksia karena terjadinya oligohidramnion yang menekan plasenta sehingga menimbulkan vasokonstriksi pembuluh darah. Penelitian ini bertujuan untuk mengetahui hubungan antara durasi KPD dengan asfiksia neonatorum di RSUD Negara pada tahun 2020.

Metode: Rancangan penelitian ini adalah analitik observasional potong lintang. Sampel penelitian adalah wanita yang terdiagnosis dengan KPD dan menjalani persalinan di RSUD Negara pada periode Januari – Desember 2020 yang dikumpulkan secara total sampling. Data durasi KPD, kejadian asfiksia neonatorum, paritas, usia maternal dan cara persalinan dikumpulkan dari rekam medis. Data kemudian dianalisis secara bivariat dengan uji Chi-square. Hubungan dikatakan signifikan bila diperoleh nilai p<0,05.

Hasil: Penelitian ini menginklusi sebanyak 220 ibu dengan KPD. Kejadian asfiksia neonatorum pada penelitian ini sebanyak 17,7%. Mayoritas pasien berusia 20-35 tahun (75,5%), memiliki paritas <2 atau >3 (79,1%), melakukan persalinan dengan tindakan (63,6%) dan memiliki durasi KPD 6-12 jam (59,5%). Durasi KPD berhubungan signifikan dengan kejadian asfiksia neonatorum (p<0,05).

Simpulan: Durasi KPD yang lebih lama berhubungan dengan kejadian asfiksia neonatorum yang lebih tinggi. Pemilihan penatalaksanaan KPD yang efektif penting untuk meminimalisasi risiko asfiksia neonatorum.

References

Lovereen S, Khanum MA, Nargis N, Begum S, Afroze R. Maternal and Neonatal outcome in premature rupture of membranes. Bangladesh J Med Sci. 2018;17(3):479–83.
Boskabadi H, Zakerihamidi M. Evaluation of Maternal Risk Factors, Delivery, and Neonatal Outcomes of Premature Rupture of Membrane: A Systematic Review Study. J Pediatr Rev. 2018;77–88.
Negara S, Mulyana R, Pangkahila E. Ketuban Pecah Dini. Buku Ajar Ketuban Pecah Dini. 2017. 1–123 p.
Wiadnya A, Surya H. Gambaran Ketuban Pecah Dini pada Kehamilan Aterm di RSUP Sanglah Tahun 2013. E-J Med Udayana. 2016;5(10):1–4.
Boskabadi H, Maamouri G, Mafinejad S. Neonatal Complications Related with Prolonged Rupture of Membranes. Maced J Med Sci. 2011;4(1):93–8.
Prawirohardjo S. Ketuban Pecah Dini. In: Ilmu Kebidanan. 4th ed. PT. Bina Pustaka Sarwono Prawirohardjo; 2010.
Begum H, Roy M, Shapla NR. Perinatal Outcome of Premature Rupture Membrane in Pregnancy. J Dhaka Med Coll. 2018;26(2):135–9.
Kardana IM. Risk Factors of Perinatal Asphyxia in The Term Newborn at Sanglah General Hospital, Bali-Indonesia. Bali Med J. 2016;5(1):196.
Woday A, Muluneh A, St Denis C. Birth asphyxia and its associated factors among newborns in public hospital, northeast Amhara, Ethiopia. PloS One. 2019;14(12):e0226891–e0226891.
Widyaningrum R, Emha M, Haderiani. Hubungan kejadian ketuban pecah dini (KPD) dengan asfiksia neonatorum di RSKIA PKU Muhammadiyah Kotagede Yogyakarta. J Kesehat Madani Med. 2020;11(1):54–62.
Endale T, Fentahun N, Gemada D, Hussen MA. Maternal and fetal outcomes in term premature rupture of membrane. World J Emerg Med. 2016;7(2):147–52.
Febriani S, Gama H, Mansyur F. Perbandingan asfiksia neonatorum pada kejadian ketuban pecah dini dan tidak ketuban pecah dini serta hasil luaran bayi di RSUD Al-Ihsan periode Januari 2016-31 Mei 2017. Pros Pendidik Dr. 2017;3(2):550–9.
Gupta S, Malik S, Gupta S. Neonatal complications in women with premature rupture of membranes (PROM) at term and near term and its correlation with time lapsed since PROM to delivery. Trop Doct. 2019;50(1):8–11.
Fattah ANA, Purwosunu Y, Sungkar A, Prameswari N. Can we predict birth asphyxia of neonates born from PPROM women? Int J Reprod Contracept Obstet Gynecol. 2017;6(10):4237.
Istiqomah S, Arun D, Widyastuti Y. Kejadian Ketuban Pecah Dini dan Kejadian Asfiksia pada Bayi Baru Lahir. Kesehat Ibu Dan Anak. 2013;4(2):51–5.
Maryuni M, Kurniasih D. Risk Factors of Premature Rupture of Membrane. Kesmas Natl Public Health J. 2017;11(3). Available from: http://dx.doi.org/10.21109/kesmas.v11i3.1153
Abdo RA, Halil HM, Kebede BA, Anshebo AA, Gejo NG. Prevalence and contributing factors of birth asphyxia among the neonates delivered at Nigist Eleni Mohammed memorial teaching hospital, Southern Ethiopia: a cross-sectional study. BMC Pregnancy Childbirth. 2019;19(1):536–536.
Mohan SS, Thippeveeranna C, Singh NN, Singh LR. Analysis of risk factors, maternal and fetal outcome of spontaneous preterm premature rupture of membranes: a cross sectional study. Int J Reprod Contracept Obstet Gynecol. 2017;6(9):3781.
Kayiga H, Lester F, Amuge PM, Byamugisha J, Autry AM. Impact of mode of delivery on pregnancy outcomes in women with premature rupture of membranes after 28 weeks of gestation in a low-resource setting: A prospective cohort study. PloS One. 2018;13(1):e0190388–e0190388.

[1] Lovereen S, Khanum MA, Nargis N, Begum S, Afroze R. Maternal and Neonatal outcome in premature rupture of membranes. Bangladesh J Med Sci. 2018;17(3):479–83.

[2] Boskabadi H, Zakerihamidi M. Evaluation of Maternal Risk Factors, Delivery, and Neonatal Outcomes of Premature Rupture of Membrane: A Systematic Review Study. J Pediatr Rev. 2018;77–88.

[3] Negara S, Mulyana R, Pangkahila E. Ketuban Pecah Dini. Buku Ajar Ketuban Pecah Dini. 2017. 1–123 p.

[4] Wiadnya A, Surya H. Gambaran Ketuban Pecah Dini pada Kehamilan Aterm di RSUP Sanglah Tahun 2013. E-J Med Udayana. 2016;5(10):1–4.

[5] Boskabadi H, Maamouri G, Mafinejad S. Neonatal Complications Related with Prolonged Rupture of Membranes. Maced J Med Sci. 2011;4(1):93–8.

[6] Prawirohardjo S. Ketuban Pecah Dini. In: Ilmu Kebidanan. 4th ed. PT. Bina Pustaka Sarwono Prawirohardjo; 2010.

[7] Begum H, Roy M, Shapla NR. Perinatal Outcome of Premature Rupture Membrane in Pregnancy. J Dhaka Med Coll. 2018;26(2):135–9.

[8] Kardana IM. Risk Factors of Perinatal Asphyxia in The Term Newborn at Sanglah General Hospital, Bali-Indonesia. Bali Med J. 2016;5(1):196.

[9] Woday A, Muluneh A, St Denis C. Birth asphyxia and its associated factors among newborns in public hospital, northeast Amhara, Ethiopia. PloS One. 2019;14(12):e0226891–e0226891.

[10] Widyaningrum R, Emha M, Haderiani. Hubungan kejadian ketuban pecah dini (KPD) dengan asfiksia neonatorum di RSKIA PKU Muhammadiyah Kotagede Yogyakarta. J Kesehat Madani Med. 2020;11(1):54–62.

[11] Endale T, Fentahun N, Gemada D, Hussen MA. Maternal and fetal outcomes in term premature rupture of membrane. World J Emerg Med. 2016;7(2):147–52.

[12] Febriani S, Gama H, Mansyur F. Perbandingan asfiksia neonatorum pada kejadian ketuban pecah dini dan tidak ketuban pecah dini serta hasil luaran bayi di RSUD Al-Ihsan periode Januari 2016-31 Mei 2017. Pros Pendidik Dr. 2017;3(2):550–9.

[13] Gupta S, Malik S, Gupta S. Neonatal complications in women with premature rupture of membranes (PROM) at term and near term and its correlation with time lapsed since PROM to delivery. Trop Doct. 2019;50(1):8–11.

[14] Fattah ANA, Purwosunu Y, Sungkar A, Prameswari N. Can we predict birth asphyxia of neonates born from PPROM women? Int J Reprod Contracept Obstet Gynecol. 2017;6(10):4237.

[15] Istiqomah S, Arun D, Widyastuti Y. Kejadian Ketuban Pecah Dini dan Kejadian Asfiksia pada Bayi Baru Lahir. Kesehat Ibu Dan Anak. 2013;4(2):51–5.

[16] Maryuni M, Kurniasih D. Risk Factors of Premature Rupture of Membrane. Kesmas Natl Public Health J. 2017;11(3). Available from: http://dx.doi.org/10.21109/kesmas.v11i3.1153

[17] Abdo RA, Halil HM, Kebede BA, Anshebo AA, Gejo NG. Prevalence and contributing factors of birth asphyxia among the neonates delivered at Nigist Eleni Mohammed memorial teaching hospital, Southern Ethiopia: a cross-sectional study. BMC Pregnancy Childbirth. 2019;19(1):536–536.

[18] Mohan SS, Thippeveeranna C, Singh NN, Singh LR. Analysis of risk factors, maternal and fetal outcome of spontaneous preterm premature rupture of membranes: a cross sectional study. Int J Reprod Contracept Obstet Gynecol. 2017;6(9):3781.

[19] Kayiga H, Lester F, Amuge PM, Byamugisha J, Autry AM. Impact of mode of delivery on pregnancy outcomes in women with premature rupture of membranes after 28 weeks of gestation in a low-resource setting: A prospective cohort study. PloS One. 2018;13(1):e0190388–e0190388.

Hubungan durasi ketuban pecah dini dengan asfiksia neonatorum di RSUD Negara tahun 2020

Abstract

References

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