Case Report

Dramatic improvement in severe-critical COVID-19 patient after tocilizumab administration: a clinical experience

Yesicha Kurniawati, Kadek Surya Atmaja , Ketut Suryana, Wayan Wahyu Semara Putra

Yesicha Kurniawati
Intern of Pulmonology and Respiratory Medicine Department, Wangaya Regional General Hospital, Denpasar, Bali, Indonesia

Kadek Surya Atmaja
Intern of Pulmonology and Respiratory Medicine Department, Wangaya Regional General Hospital, Denpasar, Bali, Indonesia. Email: suratmaja89@gmail.com

Ketut Suryana
Internist of Internal Medicine Department, Wangaya Regional General Hospital, Denpasar, Bali, Indonesia

Wayan Wahyu Semara Putra
Pulmonologist of Pulmonology and Respiratory Medicine Department, Wangaya Regional General Hospital, Denpasar, Bali, Indonesia
Online First: April 30, 2021 | Cite this Article
Kurniawati, Y., Atmaja, K., Suryana, K., Putra, W. 2021. Dramatic improvement in severe-critical COVID-19 patient after tocilizumab administration: a clinical experience. Intisari Sains Medis 12(1): 338-340. DOI:10.15562/ism.v12i1.951


Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in coronavirus disease 2019 (COVID-19) involve so many inflammatory cytokines, especially Interleukin-6 (IL-6). The usage of tocilizumab as an anti-IL-6 receptor antibody had been approved as COVID-19 medication.

Case Presentation: This article reports a 51-year-old woman diagnosed with severe-critical COVID-19. The patient made significant progress after tocilizumab administration. The patient was hospitalized for 14 days before being discharged.

Conclusion: Tocilizumab administration showed a significant improvement in COVID-19 patients.  However, further investigations are needed to explain this further.

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