Pengaruh pemberian edukasi kepada pengasuh terhadap tingkat kepatuhan pemberian obat anti epilepsi pada anak dengan epilepsi

I Gusti Ngurah Made Suwarba; Ni Made Dani Febriansiswanti; Anita Purnamayanti

doi:10.15562/ism.v12i1.892

Pengaruh pemberian edukasi kepada pengasuh terhadap tingkat kepatuhan pemberian obat anti epilepsi pada anak dengan epilepsi

I Gusti Ngurah Made Suwarba ,

Ni Made Dani Febriansiswanti ,

Anita Purnamayanti ,

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DOI: https://doi.org/10.15562/ism.v12i1.892 |
Published: 2021-04-30

Abstract

Background: Adherence was the main problem in anti-epilepsy drug therapy because it has to be consumed up to 2 years free of seizures to require education intervention. This research aimed to analyze the effect of oral and written (leaflet) education on patient carer's adherence level in administering epilepsy medicines to the pediatric patient (?18 years old).

Methods: The design of This study was one group pre - post-test research. Subjects were collected using consecutive sampling.

Results: This study's subject was 24 patient carers with low and moderate levels of medication adherence. Oral and written education material was provided every week for eight weeks, and the adherence level was analyzed through the pills count and self-report checklist every week during the study. The Wilcoxon signed-rank test results were significantly different between pre and post-pill counts, and the result of repeated measure test showed that there was an increasing level of medication adherence significantly in third obtained by pill count method week ( p=0,000 ) and remained high until the end of this study.

Conclusion: Oral and written education could improve the caregivers administering medication adherence level to their epilepsy children.

Latar belakang: Kepatuhan merupakan masalah utama dalam terapi obat anti epilepsi karena obat anti epilepsi harus dikonsumsi sampai 2 tahun bebas kejang, sehingga diperlukan edukasi. Penelitian ini bertujuan untuk menganalisis pengaruh pemberian edukasi berupa lisan dan tertulis (leaflet) terhadap tingkat kepatuhan pemberian obat oleh pengasuh kepada pasien epilepsi anak usia ?18 tahun.

Metode: Rancangan penelitian ini adalah one group pre – post test design. Pengumpulan subjek dengan consecutive sampling.

Hasil: Subjek penelitian sebanyak 24 orang dengan kriteria tingkat kepatuhan rendah dan sedang. Edukasi lisan dan tertulis diberikan setiap minggu selama 8 minggu, penilaian tingkat kepatuhan melalui pill count dan self report checklist setiap minggu selama 8 minggu. Hasil uji wilcoxon signed rank terdapat perbedaan pre pill count dan post pill count, dan hasil uji repeated measure terdapat pengaruh pemberian edukasi, yang dapat dilihat dari peningkatan nilai pill count secara signifikan pada minggu ke-3 (p=0,000) dan tetap tinggi sampai akhir penelitian.

Simpulan: Pemberian edukasi berupa lisan dan tertulis memberikan pengaruh peningkatan kepatuhan pemberian obat oleh pengasuh kepada pasien epilepsi anak.

References

Fisher RS, Cross JH, Souza CD, French JA, Haut SR, Higurashi N, et al. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia. 2017;58(4):531-42
Megiddo I, Colson A, Chisholm D, Dua T, Nandi A, Laxminarayan R. Health and economic benefits of public financing of epilepsy treatment in India: An agent- based simulation model. Epilepsia. 2016;57(3):464–74.
Suwarba IGM. Insiden dan Karakteristik Klinis Epilepsi pada Anak. Sari Pediatr. 2011;13(2):123–8.Global Asthma Network. The Global Asthma Report 2014. 2014
Access M, Use R. Report for WHO on findings of a review of existing guidance / advisory documents on how medicines should be administered to children , including general instructions on compounding preparations and manipulation of adult dosage forms. 2011;(August):1–51.
World Health Organization. Adherence to Epilepsy Therapy. 2003: 88-89 Badan Penelitian dan Pengembangan Kesehatan. Riset Kesehatan Dasar. Jakarta : Kementrian Kesehatan RI; 2013.
Camfield P, Camfiel C. Pediatric neurology principles and practice. 2006;4:981– 8.
McAuley JW, McFadden LS, Elliott JO, Shneker BF. An evaluation of self- management behaviors and medication adherence in patients with epilepsy. Epilepsy Behav. 2008;13(4):637–41.
Lukman H, Wibowo S. Hubungan Antara Kepatuhan Minum Obat Pada Penderita Epilepsi Dengan Kejadian Remisi. 2006;69.
Modi AC, Rausch JR, Glauser TA. Patterns of nonadherence to antiepileptic drug therapy in children with newly diagnosed epilepsy. Jama. 2011;305(16):1669–76.
Modi AC, Wu YP, Guilfoyle SM, Glauser TA. Uninformed clinical decisions resulting from lack of adherence assessment in children with new-onset epilepsy. Epilepsy Behav. 2012;25(4):481–4.
Aylward BS, Rausch JR, Modi AC. An examination of 1-year adherence and persistence rates to antiepileptic medication in children with newly diagnosed epilepsy. J Pediatr Psychol. 2015;40(1):66–74.
Miriam N. Non Adherence to Antiepileptic Drugs in a Child with Epilepsy : A Case Report. 2015;2(2):29–33.
Junger, Ph.D et al., The Pediatric Epillepsy Side Effects Questionairre Establishing clinically meaningful change. Elsevier Inc. 2016;8(5):583–92.
Saing JH. Tingkat Pengetahuan, Perilaku, dan Kepatuhan Berobat Orangtua dari Pasien Epilepsi Anak di Medan. 2010;12(2):103–7.
Winnick S. How Do You Improve Compliance. Pediatrics. 2005;115(6):e718–24.
Mcfarland MR, Learning B, Wehbe-alamah HB. NOT FOR SALE OR DISTRIBUTION The Theory of Culture Diversity and Universality.2006.
Penyadaran U. Bunga Rampai Upaya Penyadaran Kesehatan dan. 2009.
Morrell MJ. Gender Differences in Epilepsy. Princ Gender-Specific Med. 2004;1(6):116–28.
Notoadmojo S. Metodologi Penelitian Kesehatan. In Jakarta: PT. Rhineka Cipta; 2002.
Vinker S, Eliyahu V, Yaphe J. The effect of drug information leaflets on patient behavior. Isr Med Assoc J. 2007;9(5):383–6.
Faught E. Epilepsy & Behavior Adherence to antiepilepsy drug therapy. Epilepsy Behav [Internet]. 2012;25(3):297–302.
Jimmy B, Jose J. Patient Medication Adherence: Measures in Daily Practice. 2011;26(3):155–9.
Tanujaya, Janice T. Pengaruh Pemberian Edukasi Terhadap Ketepatan Pelaksanaan Imunisasi Dasar Pada Bayi 0-3 Bulan di Puskesmas Keputih Surabaya. Surabaya University; 2016.

[1] Fisher RS, Cross JH, Souza CD, French JA, Haut SR, Higurashi N, et al. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia. 2017;58(4):531-42

[2] Megiddo I, Colson A, Chisholm D, Dua T, Nandi A, Laxminarayan R. Health and economic benefits of public financing of epilepsy treatment in India: An agent- based simulation model. Epilepsia. 2016;57(3):464–74.

[3] Suwarba IGM. Insiden dan Karakteristik Klinis Epilepsi pada Anak. Sari Pediatr. 2011;13(2):123–8.Global Asthma Network. The Global Asthma Report 2014. 2014

[4] Access M, Use R. Report for WHO on findings of a review of existing guidance / advisory documents on how medicines should be administered to children , including general instructions on compounding preparations and manipulation of adult dosage forms. 2011;(August):1–51.

[5] World Health Organization. Adherence to Epilepsy Therapy. 2003: 88-89 Badan Penelitian dan Pengembangan Kesehatan. Riset Kesehatan Dasar. Jakarta : Kementrian Kesehatan RI; 2013.

[6] Camfield P, Camfiel C. Pediatric neurology principles and practice. 2006;4:981– 8.

[7] McAuley JW, McFadden LS, Elliott JO, Shneker BF. An evaluation of self- management behaviors and medication adherence in patients with epilepsy. Epilepsy Behav. 2008;13(4):637–41.

[8] Lukman H, Wibowo S. Hubungan Antara Kepatuhan Minum Obat Pada Penderita Epilepsi Dengan Kejadian Remisi. 2006;69.

[9] Modi AC, Rausch JR, Glauser TA. Patterns of nonadherence to antiepileptic drug therapy in children with newly diagnosed epilepsy. Jama. 2011;305(16):1669–76.

[11] Modi AC, Wu YP, Guilfoyle SM, Glauser TA. Uninformed clinical decisions resulting from lack of adherence assessment in children with new-onset epilepsy. Epilepsy Behav. 2012;25(4):481–4.

[12] Aylward BS, Rausch JR, Modi AC. An examination of 1-year adherence and persistence rates to antiepileptic medication in children with newly diagnosed epilepsy. J Pediatr Psychol. 2015;40(1):66–74.

[13] Miriam N. Non Adherence to Antiepileptic Drugs in a Child with Epilepsy : A Case Report. 2015;2(2):29–33.

[14] Junger, Ph.D et al., The Pediatric Epillepsy Side Effects Questionairre Establishing clinically meaningful change. Elsevier Inc. 2016;8(5):583–92.

[15] Saing JH. Tingkat Pengetahuan, Perilaku, dan Kepatuhan Berobat Orangtua dari Pasien Epilepsi Anak di Medan. 2010;12(2):103–7.

[16] Winnick S. How Do You Improve Compliance. Pediatrics. 2005;115(6):e718–24.

[17] Mcfarland MR, Learning B, Wehbe-alamah HB. NOT FOR SALE OR DISTRIBUTION The Theory of Culture Diversity and Universality.2006.

[18] Penyadaran U. Bunga Rampai Upaya Penyadaran Kesehatan dan. 2009.

[19] Morrell MJ. Gender Differences in Epilepsy. Princ Gender-Specific Med. 2004;1(6):116–28.

[20] Notoadmojo S. Metodologi Penelitian Kesehatan. In Jakarta: PT. Rhineka Cipta; 2002.

[21] Vinker S, Eliyahu V, Yaphe J. The effect of drug information leaflets on patient behavior. Isr Med Assoc J. 2007;9(5):383–6.

[22] Faught E. Epilepsy & Behavior Adherence to antiepilepsy drug therapy. Epilepsy Behav [Internet]. 2012;25(3):297–302.

[23] Jimmy B, Jose J. Patient Medication Adherence: Measures in Daily Practice. 2011;26(3):155–9.

[24] Tanujaya, Janice T. Pengaruh Pemberian Edukasi Terhadap Ketepatan Pelaksanaan Imunisasi Dasar Pada Bayi 0-3 Bulan di Puskesmas Keputih Surabaya. Surabaya University; 2016.

Pengaruh pemberian edukasi kepada pengasuh terhadap tingkat kepatuhan pemberian obat anti epilepsi pada anak dengan epilepsi

Abstract

References

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