Research Article

DOI: 10.15562/ism.v11i3.871

Hubungan berat badan lahir rendah dengan asfiksia neonatorum di Rumah Sakit Umum (RSU) Negara

Made Dwitia Ayu Iswari , I Gusti Ketut Winata Adnyana

Made Dwitia Ayu Iswari
Dokter Internship, Rumah Sakit Umum (RSU) Negara, Jembrana, Bali. Email: dwitiai@gmail.com

I Gusti Ketut Winata Adnyana
Bagian Ilmu Kesehatan Anak, Rumah Sakit Umum (RSU) Negara, Jembrana, Bali
Online First: December 01, 2020 | Cite this Article
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Iswari, M., Adnyana, I. 2020. Hubungan berat badan lahir rendah dengan asfiksia neonatorum di Rumah Sakit Umum (RSU) Negara. Intisari Sains Medis 11(3): 1510-1514. DOI:10.15562/ism.v11i3.871


Background: low birth weight is one of the mortality causes in neonates. This condition is associated with organ immaturity including lung and inadequate surfactant in alveolus which increase the risk of asphyxia neonatorum.The aim of this study is to know the correlation between low birth weight and asphyxia neonatorum in RSU Negara.

Methods: The design of this study was observational analytic cross-sectional. Neonates, who were hospitalized in NICU and perinatology RSU Negara, Jembrana in August 2019-August 2020 were assigned by systematic random sampling. Data was collected from medical records. Then, data was analyzed using chi-square test and logistic regression test to get prevalence ratio (PR). The value of p<0.05 was considered significant.

Result: As many as 150 neonates were recruited in the study. A multivariate analysis showed the prevalence of asphyxia neonatorum was significantly higher in low birth weight neonates (PR=2.331, p=0.045; IK 95% 1.018-5.338) than non-low birth weight neonates. There were no association between asphyxia neonatorum and prematurity, mode of delivery and sex of newborn.

Conclusion: low birth weight is associated with asphyxia neonatorum.

 

 

Latar Belakang: Berat badan lahir rendah merupakan salah satu penyebab kematian neonatus. Kondisi ini disertai dengan imaturitas organ tubuh termasuk paru-paru dan kurangnya surfaktan dalam alveolus sehingga meningkatkan risiko terjadinya asfiksia neonatorum. Tujuan penelitian ini adalah untuk mengetahui hubungan antara berat badan lahir rendah dan asfiksia neonatorum di RSU Negara.

Metode: penelitian ini menggunakan rancangan analitik observasional potong-lintang. Neonatus yang dirawat di Bagian NICU dan perinatologi RSU Negara, Jembrana dalam kurun waktu Agustus 2019 – Agustus 2020 yang dikumpulkan secara systematic random sampling. Data dikumpulkan dari rekam medis. Data kemudian dianalisis secara bivariat dengan uji chi-square dan multivariat dengan uji regresi logistik sehingga diperoleh prevalence ratio (PR). Hubungan dikatakan signifikan apabila diperoleh nilai p< 0,05.

Hasil: penelitian ini mengikutsertakan sebanyak 150 neonatus. Berdasarkan hasil uji multivariat, prevalensi kejadian asfiksia neonatorum lebih tinggi pada neonatus dengan BBLR (PR=2,331, p=0,045; IK 95% 1,018-5,338) dibandingkan dengan yang tidak mengalami BBLR. Tidak ada perbedaan kejadian asfiksia berdasarkan prematuritas, cara persalinan, dan jenis kelamin bayi.

Simpulan: berat badan lahir rendah berhubungan dengan asfiksia neonatorum

References

Gillam-Krakauer M, Gowen Jr CW. Birth Asphyxia. 2020. [Online]. Treasure Island (FL): StatPearls Publishing. Tersedia pada: https://www.ncbi.nlm.nih.gov/books/NBK430782/. Diakses pada: 01 Oktober 2020

Departemen Kesehatan RI. Riset Kesehatan Dasar. Jakarta: Badan Penelitian dan pengembangan Kesehatan Kementerian Kesehatan RI. 2013

World Health Organization. MCEE-WHO methods and data sources for child causes of death 2000–2015 (Global Health Estimates Technical Paper WHO/HIS/HSI/GHE/2016.1). Geneva: Department of Information, Evidence and Research WHO. 2016

WHO. Global Nutrition Target 2025: Low Birth Weight Policy Brief. Geneva. 2014

Ikatan Dokter Anak Indonesia (IDAI). Pedoman Pelayanan Medis Ikatan Dokter Anak Indonesia. Jakarta. 2009

Wiadnyana, I., Bikin Suryawan, I. and Sucipta, A. Hubungan antara bayi berat lahir rendah dengan asfiksia neonatorum di RSUD Wangaya Kota Denpasar. Intisari Sains Medis. 2018; 9(2).

Utomo MT. Risk Factors for Birth Asphyxia. Folia Medica Indonesiana. 2011; 47(4): 211-214

Yanti SJ, Sari DN. Hubungan Berat Badan Lahir Rendah (BBLR) dengan Asfiksia Neonatorum di RSUD Arifin Achmad. Keskom. 2017; 3(5): 189-192

Nayeri F, Shariar M, Dalili H, dkk. Perinatal risk factors for neonatal asphyxia in Vali-e-Asr hospital, Tehran-Iran. Iran J Reprod Med. 2012; 10(2): 137-140

Tasew H, Zemicheal M, Teklay G. Risk Factors of Birth Asphyxia among newborns in public hospital of Central Zone, Tigray, Ethiopia 2018. BMC Res Notes. 2018; 11: 496

Gebreheat G, Tsegay T, Kiros D, dkk. Prevalence and Associated Factors of Perinatal Asphyxia among Neonates in General Hospital of Tigray, Ethiopia, 2018. Biomed Research International. 2018. Hal: 1-8

Aslam HM, Saleem S, Afzal R, dkk. Risk factors of birth asphyxia. Italian Journal of Pediatrics. 2014;1-9

Kusumaningrum RY, Murti B, Prasetya H. Low Birth, Prematurity, and Pre-Eclampsia as Risk Factors of Neonatal Asphyxia. Journal of Maternal and Child Health. 2019; 4(1): 49-54

Putra PJ. Characteristics and Outcomes of Low Birth Weight Infants in Bali. Paediatr Indones. 2012; 52(5): 300-303

Opitasari C. Maternal education, prematurity, and the risk of birth asphyxia in selected hospital in Jakarta. Health Science Journal of Indonesia. 2015; 6(2): 111-115

Abdo RA, Halil HM, Kebede BA, dkk. Prevalence and contributing factors of Birth asphyxia among the neonates delivered at Negest Eleni Mohammed memorial teaching hospital, Southern Ethiopia: A cross-sectional study. BMC Pregnancy and Childbirth. 2019;19(536).

Woday A, Muluneh A, St Denis C. Birth asphyxia and its associated factors among newborns in public hospital, northeast Amhara, Ethiopia. PLoS ONE. 2019; 14(12): e0226891.

Utomo MT. Risk factors for birth asphyxia. Folia Medica Indonesiana.2011; 47(4):211-214.

Kardana IM. Risk factors of perinatal asphyxia in the term newborn at sanglah general hospital, bali-indonesia. Bali Med J. 2016; 5(1): 196-199


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