Review Article

Graves’ disease: A review in diagnosis and management

I Gusti Hindra Dwisaputra, I Made Yoga Prabawa

I Gusti Hindra Dwisaputra
Medical Doctor, Faculty of Medicine, Universitas Udayana, Bali, Indonesia

I Made Yoga Prabawa
Medical Doctor, Faculty of Medicine, Universitas Udayana, Bali, Indonesia. Email:
Online First: December 01, 2020 | Cite this Article
Dwisaputra, I., Prabawa, I. 2020. Graves’ disease: A review in diagnosis and management. Intisari Sains Medis 11(3): 793-797. DOI:10.15562/ism.v11i3.762

Background: Graves’ disease is the leading cause of hyperthyroidism condition in the world. The incidence of Graves’ disease in the world reaches 20-50 cases per 100,000 population per year. Graves’ disease can cause somatic, psychiatric, and cosmetic problems in the patient. In some cases, it caused a decreased quality of life and death if not appropriately managed. Hence, appropriate diagnosis and management should be made to prevent the progression of the disease.

Aim: This literature review aims to review the diagnosis and management of Graves’ disease.

Conclusion: Graves’ disease is an autoimmune disease that causes hyperthyroidism by stimulating the thyroid gland to produce thyroid hormone. History taking and laboratory investigation can be done to establish a diagnose of Graves’ disease. Treatment, including the use of anti-thyroid drugs, radioiodine therapy, and surgery. Monitoring should be done periodically during and after the course of treatment to prevent relapse.


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