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Efektivitas multi drug therapy pada transmisi morbus hansen transplasental

  • Dhelya Widasmara ,
  • Santosa Basuki ,
  • Dea Florensia ,
  • Ade Setyagraha ,
  • Nugrahanti Prasetyorini ,

Abstract

Introduction: The evidence of transplancental transmission of Morbus Hansen (MH) in animal models is a challenge for MH treatment in pregnancy because it brings anxiety for patients and their fetuses. 

Case: A 31-year-old pregnant woman, first trimester, came with complaints of reddish numbness rash on her hands since 2 years ago. Dermatological examination showed erythematous plaque, multiple, well-defined, irregular borders with hypoaesthesia. There were right and left ulnar nerve enlargement. Acid Fast Bacteria (AFB) from ear lobes and lesion revealed Bacterial Index +2 and Morphological Index 10%. Histopathological examination showed gren zone which indicate MH type BL. Patient was diagnosed with MH Multi Basiler (MB) on G3P2002Ab000 and given MDT MHMB. Postpartum IgM and IgG anti-PGL-1 examination of cord blood and infant blood, also PCR examination of cord blood and amnion showed negative results. Histopathological examination found no AFB on the umbilical cord and placenta. 

Conclusion: MDT is effective in preventing transplacental transmission of MH from mother to fetus.

References

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How to Cite

Widasmara, D., Basuki, S., Florensia, D., Setyagraha, A., & Prasetyorini, N. (2020). Efektivitas multi drug therapy pada transmisi morbus hansen transplasental. Intisari Sains Medis, 11(2), 425–428. https://doi.org/10.15562/ism.v11i2.713

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