Case Report

Efektivitas multi drug therapy pada transmisi morbus hansen transplasental

Dhelya Widasmara , Santosa Basuki, Dea Florensia, Ade Setyagraha, Nugrahanti Prasetyorini

Dhelya Widasmara
Departemen/SMF Dermatologi dan Venereologi, Fakultas Kedokteran Universitas Brawijaya/ Rumah Sakit Umum Daerah Dr. Saiful Anwar, Malang, Indonesia. Email: dhelyawidasmara@ub.ac.id

Santosa Basuki
Departemen/SMF Dermatologi dan Venereologi, Fakultas Kedokteran Universitas Brawijaya/ Rumah Sakit Umum Daerah Dr. Saiful Anwar, Malang, Indonesia

Dea Florensia
Departemen/SMF Dermatologi dan Venereologi, Fakultas Kedokteran Universitas Brawijaya/ Rumah Sakit Umum Daerah Dr. Saiful Anwar, Malang, Indonesia

Ade Setyagraha
Departemen/SMF Obstetri Ginekologi, Fakultas Kedokteran Universitas Brawijaya/ Rumah Sakit Umum Daerah Dr. Saiful Anwar, Malang, Indonesia

Nugrahanti Prasetyorini
Departemen/SMF Obstetri Ginekologi, Fakultas Kedokteran Universitas Brawijaya/ Rumah Sakit Umum Daerah Dr. Saiful Anwar, Malang, Indonesia
Online First: May 21, 2020 | Cite this Article
Widasmara, D., Basuki, S., Florensia, D., Setyagraha, A., Prasetyorini, N. 2020. Efektivitas multi drug therapy pada transmisi morbus hansen transplasental. Intisari Sains Medis 11(2): 425-428. DOI:10.15562/ism.v11i2.713


Introduction: The evidence of transplancental transmission of Morbus Hansen (MH) in animal models is a challenge for MH treatment in pregnancy because it brings anxiety for patients and their fetuses. 

Case: A 31-year-old pregnant woman, first trimester, came with complaints of reddish numbness rash on her hands since 2 years ago. Dermatological examination showed erythematous plaque, multiple, well-defined, irregular borders with hypoaesthesia. There were right and left ulnar nerve enlargement. Acid Fast Bacteria (AFB) from ear lobes and lesion revealed Bacterial Index +2 and Morphological Index 10%. Histopathological examination showed gren zone which indicate MH type BL. Patient was diagnosed with MH Multi Basiler (MB) on G3P2002Ab000 and given MDT MHMB. Postpartum IgM and IgG anti-PGL-1 examination of cord blood and infant blood, also PCR examination of cord blood and amnion showed negative results. Histopathological examination found no AFB on the umbilical cord and placenta. 

Conclusion: MDT is effective in preventing transplacental transmission of MH from mother to fetus.

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