Skip to main content Skip to main navigation menu Skip to site footer

The correlation between location and size of infarction toward the quality of life in acute ischemic stroke patients at Sanglah General Hospital, Bali, Indonesia



Abstract

Background: Location and size of infarction in acute ischemic stroke can cause different levels of neurological deficits and disabilities according to the function of the area of brain whose blood flow is disrupted, thus affecting the quality of life in patients. This study was aimed to explore the correlation between location and size of infarction toward the quality of life in acute ischemic stroke patients in SanglahเGeneralเHospitalเDenpasar.

Methods: A cross-sectional study was conducted among 41 acute ischemic stroke patients at NeurologyเCare Unit, SanglahเGeneral Hospital Denpasar duringเMay-September 2019. The location of the infarct was grouped by the cerebral area. The largest diameter of infarction determined the size of the infarct. Data were taken from head ComputedเTomography (CT) scan results to assess the location and size of infarction and Barthel Index (BI) to measure the quality of life-based on Activity of Daily Living (ADL). Data were analyzed using univariate and bivariate analysisเ(Chi-SquareเtestเwithเCramer’sเV for location and BI scores, Spearmanเtest for size and BI scores) on SPSSเversion 23 for Windows.

Results: Most of the respondents were males 59.0%, the average age of 60.03±14.4 years, ischemic thrombus stroke (71.8%), subcortical infarction (41.0%), small size (≤ 1.5 cm) of infarction (48.7%), and independent criteria for Barthel Index Scores (23.1%). There were significant correlations between the location of infarction and BI scores (r=0.636; p<0.000) and the size of infarction and BI scores (r=0.553; p<0.000).

Conclusion: Infarct that located in the cortical area with small size are related to independent or mild dependency outcome. Conversely, infarct that located and associated with a subcortical area with larger size are related to severe or total dependency.

Keywords: Ischemic Stroke Infarct Location Infarct Size Barthel Index Scores

References

  1. Sacco RL, Kasner SE, Broderick JP, Caplan LR, Connors JJB, Culebras A, et al. An updated definition of stroke for the 21st century: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2013;44(7):2064-2089.
  2. Kanyal N. The Science of Ischemic Stroke: Pathophysiology & Pharmacological Treatment. IJPRR.เ2015;4(10):65-84.
  3. Caplan LR, Wong KS, Gao S, Hennerici MG. Is hypoperfusion an important cause of strokes? If so, how?. Cerebrovasc Dis. 2006;21(3):145-153.
  4. Pan SL, Wu SC, Wu TH, Lee TK, Chen TH. Location and size of infarct on functional outcome of noncardioembolic ischemic stroke. Disabil Rehabil. 2006;28(16):977-983.
  5. López-Espuela F, Pedrera-Zamorano JD, Jiménez-Caballero PE, Ramirez-Moreno JM, Portilla-Cuenca JC, Lavado-Garcia JM, et al. Functional Status and Disability in Patients After Acute Stroke: A Longitudinal Study. Am J Crit Care. 2016;25(2):144-151.
  6. Quinn TJ, Langhorne P, Stott DJ. Barthel index for stroke trials: development, properties, and application. Stroke. 2011;42(4):1146-1151.
  7. Hussain Z, Hilal K, Ahmad M, Sajjad Z, Sayani R. Clinicoradiological Correlation of Infarct Patterns on Diffusion-weighted Magnetic Resonance Imaging in Stroke. Cureus. 2018;10(3):e2260.
  8. Yong SW, Bang OY, Lee PH, Li WY. Internal and cortical border-zone infarction: clinical and diffusion-weighted imaging features. Stroke. 2006;37(3):841-846.
  9. Dhamoon MS, Cheung YK, DeRosa JT, Gutierrez J, Moon YP, Sacco RL, et al. Association Between Subclinical Brain Infarcts and Functional Decline Trajectories. J Am Geriatr Soc. 2018;66(11):2144-2150.
  10. Nazzal ME, Saadah MA, Saadah LM, Trebinjac SM. Acute ischemic stroke: relationship of brain lesion location & functional outcome. Disabil Rehabil. 2009;31(18):1501-1506.
  11. Kalowska E, Rostrup E, Rosenbaum S, Petersen P, Paulson OB. Acute MRI changes in progressive ischemic stroke. Eur Neurol. 2008;59(5):229-236.
  12. Barrett KM, Ding YH, Wagner DP, Kallmes DF, Johnston KC; ASAP Investigators. Change in diffusion-weighted imaging infarct volume predicts neurologic outcome at 90 days: results of the Acute Stroke Accurate Prediction (ASAP) trial serial imaging substudy. Stroke. 2009;40(7):2422-2427.
  13. Yuantari R, Wuriyanti D, Siswantoro D. The correlation of Lipoprotein (a) with the severity of ischemic stroke in Dr. Soedono General Hospital, Madiun, Indonesia. Bali Medical Journal. 2019;8(1):275-280.

How to Cite

Yusrika, M. U., Nuartha, A. A. B. N., Wijayanti, I. A. S., Asih, M. W., & Sujatmiko, S. S. (2020). The correlation between location and size of infarction toward the quality of life in acute ischemic stroke patients at Sanglah General Hospital, Bali, Indonesia. Intisari Sains Medis, 11(2), 717–721. https://doi.org/10.15562/ism.v11i2.675
ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver
Download Citation
Endnote/Zotero/Mendeley (RIS) BibTeX

HTML
179

Total
192

Share

Search Panel

Mirani Ulfa Yusrika
Google Scholar
Pubmed
ISM Journal

Anak Agung Bagus Ngurah Nuartha
Google Scholar
Pubmed
ISM Journal

Ida Ayu Sri Wijayanti
Google Scholar
Pubmed
ISM Journal

Made Widhi Asih
Google Scholar
Pubmed
ISM Journal

Skolastika Savitri Sujatmiko
Google Scholar
Pubmed
ISM Journal