Research Article

Prevalensi gambaran faktor risiko penyakit jantung koroner pada pasien diabetes melitus tipe-2 di RSUP Sanglah Denpasar periode 2015

Ni Putu Widya Nandasari , Desak Gde Diah Dharma Santhi, I Wayan Putu Sutirta Yasa

Ni Putu Widya Nandasari
Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Udayana. Email: nandasari29@gmail.com

Desak Gde Diah Dharma Santhi
Bagian/KSM Patologi Klinik RSUP Sanglah Denpasar

I Wayan Putu Sutirta Yasa
Bagian/KSM Patologi Klinik RSUP Sanglah Denpasar
Online First: August 01, 2020 | Cite this Article
Nandasari, N., Santhi, D., Yasa, I. 2020. Prevalensi gambaran faktor risiko penyakit jantung koroner pada pasien diabetes melitus tipe-2 di RSUP Sanglah Denpasar periode 2015. Intisari Sains Medis 11(2): 484-488. DOI:10.15562/ism.v11i2.616


Introduction: The main causes of mortality and morbidity in patients with Type-2 Diabetes Melitus (T2DM) is coronary heart disease. This study aims to describe various risk factors for coronary heart disease, modified and unmodified included among patients with T2DM in Sanglah General Hospital, within 2015.

Method: The research uses descriptive cross-sectional design with total sampling technique has been used as sampling method. Data was taken from patients’s medical record within the period of January to December 2015. It was processed using SPSS 21 and presented in a frequency distribution table and crosstabulation based on risk factors. Around 48 samples which met the criteria were included in this study.

Result: It was obtained that the prevalence of the unmodified risk factors of CHD in T2DM were male gender (87.5%) and aged ≥45 years old (95.8%). The modified factors are fasting blood glucose ≥126 mg/dL (83.3%), body mass index ≥25 kg/m2 (64.6%), random blood glucose ≥200 mg/dL (58.3%), HDL ≤45 mg/dL (41.7%), triglycerides ≥150 mg/dL (22.9%), blood pressure ≥140/90 mmHg (22.9%), total cholesterol ≥200 mg/dL (22.9%), and LDL ≥160 mm/dL (8.3%).

Conclusion: It can be concluded that men with age ≥45 years, fasting blood glucose, body mass index, and uncontrolled random blood glucose are risk factor for CHD in T2DM in Sanglah Hospital. Therefore, monitoring of blood sugar levels and body mass index in patients with T2DM are necessary to prevent CHD.

 

Latar Belakang: Penyebab mortalitas dan morbiditas utama pada pasien Diabetes Melitus Tipe-2 (DMT2) adalah penyakit jantung coroner (PJK). Penelitian ini bertujuan untuk mengetahui gambaran berbagai faktor risiko penyakit jantung koroner yang tidak dapat diubah dan dapat diubah pada penderita DMT2 di Rumah Sakit Umum Pusat Sanglah periode 2015. Metode: Penelitian menggunakan desain deskriptif cross-sectional, dan pengambilan sampel dilakukan dengan teknik total sampling. Data diambil berdasarkan rekam medis pasien periode Januari – Desember 2015. Kemudian data diolah menggunakan SPSS 21, dan disajikan dalam bentuk tabel distribusi frekuensi dan crosstabulation berdasarkan faktor risiko.

Hasil: Didapatkan sebanyak 48 sampel penelitian yang memenuhi kriteria dan dapat digunakan dalam studi ini, diperoleh prevalensi gambaran faktor risiko PJK pada DMT2 yang tidak dapat diubah adalah jenis kelamin laki-laki (87,5%) dan usia ≥45 tahun (95,8%). Faktor yang dapat diubah seperti gula darah puasa ≥126 mg/dL (83,3%), indeks masa tubuh ≥25 kg/m2 (64,6%), gula darah sewaktu ≥200 mg/dL (58,3%), HDL ≤45 mg/dL (41,7%), trigliserida ≥150 mg/dL (22,9%), tekanan darah ≥140/90 mmHg (22,9%), kolesterol total ≥200 mg/dL (22,9%), dan LDL ≥160 mm/dL (8,3%).

Conclusion: Laki-laki dengan usia ≥45 tahun, gula darah puasa, indeks masa tubuh, dan gula darah sewaktu yang tidak terkontrol merupakan faktor risiko untuk terjadinya PJK pada DMT2 di RSUP Sanglah. Sehingga diperlukan pengawasan kadar gula darah dan indeks masa tubuh pada pasien DMT2 agar tidak terjadi PJK.

References

American Diabetes Association (ADA). Standards of Medical Care in Diabetes-2019 abdridge for Primary Care Providers. Clinical Diabetes. 2019;37(1):11-34.

Gamayanti K, Ratnasari N, Bhargah A. Pola penggunaan insulin pada pasien diabetes mellitus tipe 2 di poli penyakit dalam RSU Negara Periode Juli – Agustus 2018. Intisari Sains Medis. 2018;9(3):68-73. DOI:10.15562/ism.v9i3.306

American Diabetes Association (ADA). Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 2011;33(Suppl 1):S62-S69.

Kirthi A, Yasmin A, Artha I, Bhargah A. Hipertensi sebagai prediktor kejadian kardiovaskular mayor pada pasien infark miokard akut pada tahun 2018 di RSUP Sanglah Denpasar, Bali-Indonesia. Intisari Sains Medis. 2019;10(3):530-536. DOI:10.15562/ism.v10i3.443

Artha IMJR, Bhargah A, Dharmawan NK, et al. High level of individual lipid profile and lipid ratio as a predictive marker of poor glycemic control in type-2 diabetes mellitus. Vasc Health Risk Manag. 2019;15:149–157. doi:10.2147/VHRM.S209830.

Naito R, Kasai T. Coronary artery disease in type 2 diabetes mellitus: recent treatmemt strategies and future perspective. World J Cardiol. 2015;7(3):119-124.

Martin I, Collantes C, Galindo A, Gomez F. Type 2 diabetes and cardiovascular disease: Have all risk factors the same strength. World J Diabetes. 2014;5(4):444-470

Einarson T, Acs A, Ludwig C. Prevalence of cardiovascular disease in type 2 diabetes: a systematic literature review of scientific evidence from across the world in 2007-2017. Cardiovasc Diabetol. 2018;17:83-89.

Srinavasan M, et.al. Correlation of severity of coronary artery disease with insulin resistance. N Am J Med Sci. 2013;5(10):611-14.

Bertolouchi M, Rocha V. Cardiovascular risk assessment in patients with diabetes. Diabetol Metab Syndr. 2017;9:25-32.

Dousi C, Cassom I, Farlane I, et al. Prevalence of obesity in type 2 diabetes in secondary care: association with cardiovascular risk factors. Postgrad Med J. 2006; 82(96):280-4.

De Rosa S, Arcidiacono B, Chiefari E, Brunetti A, Indolfi C, Foti D. Type 2 Diabetes Melitus and Cardiovascular Disease: Genetic and Epigenetic Links. Front Endrocinol. 2018;9:2-8.

Zitnanova I, et al. Gender differences in LDL and HDL cholesterol subfractions in patients after the acute ischemic stroke and their association with oxidative stress markers. J Clin Biochem Nutr. 2018;63(2):144-48.

Gupta R, et al. Gender differences in 7 years trends in cholesterol lipoproteins and lipids in India: Insights from a hospital database. Indian J Endocrinol Metab. 2016; 20(2):211-8.


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