Research Article

Berat badan lahir lebih dari 4000 gram merupakan faktor risiko kejadian mikropenis pada bayi baru lahir di Denpasar tahun 2019

I Gusti Bagus Dharma Prakasa Musti , Gede Wirya Kusuma Duarsa, Tjok Gde Mahadewa, Gede Wirata

I Gusti Bagus Dharma Prakasa Musti
Departemen Ilmu Bedah, Fakultas Kedokteran Universitas Udayana, Rumah Sakit Umum Pusat Sanglah Denpasar, Bali. Email: dharma.prakasa@gmail.com

Gede Wirya Kusuma Duarsa
Departemen Ilmu Bedah, Fakultas Kedokteran Universitas Udayana, Rumah Sakit Umum Pusat Sanglah Denpasar, Bali

Tjok Gde Mahadewa
Departemen Ilmu Bedah Saraf, Fakultas Kedokteran Universitas Udayana/RSUP Sanglah Denpasar Bali

Gede Wirata
Departemen Anatomi, Fakultas Kedokteran Universitas Udayana
Online First: December 09, 2019 | Cite this Article
Musti, I., Duarsa, G., Mahadewa, T., Wirata, G. 2019. Berat badan lahir lebih dari 4000 gram merupakan faktor risiko kejadian mikropenis pada bayi baru lahir di Denpasar tahun 2019. Intisari Sains Medis 10(3). DOI:10.15562/ism.v10i3.577


Background: Standard values related to age for penis size can help for early diagnosis and treatment of potential diseases. Rapid changes in growth and interindividual differences can occur during infancy and puberty. Therefore, micropenis data during newborns are beneficial for clinical evaluation and prognosis.

Aim: This study aims to find out whether birth weight > 4000 grams and testis size <0.52 cm are risk factors for micropenis prevalence in newborns.

Methods: This study used a descriptive-analytical cohort study involving 85 research subjects, namely healthy newborn boys who did not experience hypospadias, severe chordae, ambiguous penises. Respondents contributed to physical examinations and investigations following the standard procedure in the analysis of the weight, gestational age, and size of the testis. The study also evaluated the risk factors for micropenis in the form of a history of maternal hormonal birth control.

Results: The micropenis was categorised to be <1.8 cm, which was obtained from <2.5 SD mean where the size of penis length in this study was achieved with a mean of 2.08 cm. The results of the multi-variate test showed that birth weight> 4000 grams was the most dominant risk factor causing micropenis. The positive B value with a value of 5.13, which means birth weight> 4000 grams has a positive relationship with the incidence of micropenis. The newborn weight was obtained about p = 0,000 (95%CI: 11,29-2558,17) with OR 170 which mean that there was an effect of birth weight on the incidence of micropenis where birth weight> 4000 grams had a chance of micropenis by 170 times.

Conclusion: Weight> 4000 grams became the most dominant risk factor for micropenis having probabilities for a micropenis approximately 170 times.

References

Saputra, MAR & Tanzila, RA. Angka Kejadian Mikropenis pada Anak Usia 3-5 Tahun di TK Chiqia Smart dan TK Al Fashtha Palembang Tahun 2014. Badian Biologi Kedokteran Fakultas Kedokteran UNSRI. 2017; 5 (2).

Dharmika, IAGW, Negara, MO, Kurniawan, Y. Hubungan obesitas sentral dengan testosterone deficiency syndrome (TDS) pada laki-laki dewasa di Denpasar tahun 2017. Bali Anatomy Journal. 2018; 1 (2): 35-38.

Widianti, I.G.A., Wardana, I.N.G., Wirata, G. 2018. Sweet pranajiwa (Sterculia javanica R. Br) seed extract increases spermatogenesis and sexual behavior in mice (Mus musculus). IJBS 12(1): 7-12. DOI:10.15562/ijbs.v12i1.149

Wardana, I.N.G., Widianti, I.G.A., Wirata, G. 2018. Testosterone increases corpus cavernous smooth muscle cells in oxidative stress-induced rodents (Sprague-Dawley). Bali Medical Journal 7(2): 313-322. DOI:10.15562/bmj.v7i2.970

Supriatmo & Siregar, CD. Mikropenis. Sari Pediatri, Maret 2014; 5(4): 145-149

Ponchietti R, Mondaini N, Bonafè M, Di Loro F, Biscioni S, Masieri L. Penile length and circumference: a study on 3,300 young Italian males. Eur Urol. 2001; 39: 183-6.

Çamurdan A, Mustafa OÖ, Mustafa N, Ilhan, Orhun M, Çamurdan FS, et al. Current stretched penile length: crosssectional study of 1040 healthy Turkish children aged 0 to 5 years. Urology. 2007;70:572–5

Tamova, A, Depinder F, Robeva, R. Growth and Development of Male Eksternal Genetalia. American Medical Association; 2011.

Halil, H & Oğuz, SS. Establishment of normative data for stretched penile length in Turkish preterm and term newborns. The Turkish Journal of Pediatrics 2017; 59: 269-273

Park JY, Lim G, Oh KW, Ryu DS, Park S, Jeon JC, et al. Penile length, digit length, and anogenital distance according to birth weight in newborn male infants. Korean J Urol 2015;56:248-253

Akın Y, Ercan O, Telatar B, Tarhan F. Penile size in term newborn infants. The Turkish Journal of Pediatrics 2011; 53: 301-307

Hatipoglu, N & Kurtoglu, S. Micropenis: Etiology, Diagnosis and Treatment Approaches. J Clin Res Pedíatri Endocrinol. 2013; 5(4): 217-223.

Irfon R, Karmaya INM, Yuliana. Aktivitas fisik moderat meningkatkan rasio jumlah otot polos dan kolagen pada penis tikus tua (Rattus norvegicus). Bali Anatomy Journal. 2018; 1(1): 1-4


No Supplementary Material available for this article.
Article Views      : 15
PDF Downloads : 2