Research Article

Karakteristik gambaran sitologi pap-smear sebagai tes skrining untuk lesi pra-kanker serviks di RSUP Sanglah, Denpasar, Bali

Putu Risky Yoga Pradnyana , Anak Agung Ayu Ngurah Susraini, I Gusti Ayu Sri Mahendra Dewi

Putu Risky Yoga Pradnyana
Program Studi Sarjana Kedokteran dan Profesi Dokter, Fakultas Kedokteran Universitas Udayana, Bali, Indonesia. Email: riskyyoga69@gmail.com

Anak Agung Ayu Ngurah Susraini
SMF Patologi Anatomi, Fakultas Kedokteran Universitas Udayana, RSUP Sanglah Denpasar, Bali, Indonesia

I Gusti Ayu Sri Mahendra Dewi
SMF Patologi Anatomi, Fakultas Kedokteran Universitas Udayana, RSUP Sanglah Denpasar, Bali, Indonesia
Online First: December 01, 2019 | Cite this Article
Pradnyana, P., Susraini, A., Dewi, I. 2019. Karakteristik gambaran sitologi pap-smear sebagai tes skrining untuk lesi pra-kanker serviks di RSUP Sanglah, Denpasar, Bali. Intisari Sains Medis 10(3). DOI:10.15562/ism.v10i3.461


Background: Cervical cancer is the second most often cancer that occurs in women worldwide after breast cancer and as many as 84% of the cases occur in developing countries. Pap Smear is a screening method that widely used for cervical cancer screening. The aim of the study is to obtain the characteristic data of pap smear cytology as a pre-cervical cancer screening in Sanglah General Hospital 2016 – 2017 period.

Methods: This study was descriptive research with cross sectional study design. The sampling technique is total sampling where the research data comes from the cytology registration book results of the Anatomical Pathology Laboratory at Sanglah General Hospital Denpasar 1 January 2016 - 31 December 2017 period which has fulfilled the inclusion criteria and does not meet the exclusion criteria. Data were analyzed using SPSS version 20 for Windows.

Results: This study collected as many as 590 samples. Most of the pap smear patients at Sanglah General Hospital Denpasar were 41-50 year old group as many as 188 people (31.86%), most of the patients parities were nullipara parities as many as 324 people (54.92%), most had no complaints as many as 261 people (44.24%) and most of the pap smear cytology description was Reactive Cellular Changes Associated with Inflammation (RCCI) as many as 261 people (44.64%).

Conclusion: Most of the respondents who underwent pap-smear test as a screening step for pre-cancerous lesions had a cytological picture of Reactive cellular changes associated with Inflammation (RCCI)

References

Steben M, Duarte-Franco E. Human papillomavirus infection: epidemiology and pathophysiology. Gynecol Oncol. 2007;107(2 Suppl 1):S2-5.

Gillison ML, Castellsagué X, Chaturvedi A, Goodman MT, Snijders P, Tommasino M, et al. Eurogin Roadmap: comparative epidemiology of HPV infectionand associated cancers of the head and neck and cervix. Int J Cancer. 2014 Feb 1;134(3):497-507.

Wiebe E, Denny L, Thomas G. Cancer of the cervix uteri. Int J Gynaecol Obstet. 2012;119 Suppl 2:S100-9.

Prat J. Pathology of cancers of the female genital tract. Int J Gynaecol Obstet. 2015;131 Suppl 2:S132-45.

Rasjidi I. Epidemiologi Kanker Serviks. Indonesian Journal of Cancer. 2009;3(3):103–108.

Prabawa IPY, Bhargah A, Liwang F, Tandio DA, Tandio AL, Lestari AAW, et al. Pretreatment Neutrophil-to-Lymphocyte ratio (NLR) and Platelet-to-Lymphocyte Ratio (PLR) as a Predictive Value of Hematological Markers in Cervical Cancer. Asian Pac J Cancer Prev. 2019;20(3):863-868.

Mastutik G, Alia R, Rahniayu A, Kurniasari N, Rahaju AS, Mustokoweni S. Skrining Kanker Serviks dengan Pemeriksaan Pap Smear di Puskesmas Tanah Kali Kedinding Surabaya dan Rumah Sakit Mawadah Mojokerto. Majalah Obstetri & Ginekologi. 2015;23(2):54-60

Deas P, Ade W, Sofian A. Gambaran hasil pemeriksaan sitologi serviks wanita pekerja seksual tidak langsung pada Hotspot X Kecamatan Payung Sekaki Pekanbaru Putri. Jom FK. 2016;3(1):1–14.

Rahmadani FT, Ade W, Sofian A. Gambaran Hasil Sitologi Serviks Wanita Pekerja Seksual Tidak Langsung Pada Hotspot X Kecamatan Marpoyan Damai Pekanbaru. Jom FK. 2016;3(2):1-12

Verma A, Verma S, Vashist S, Attri S, Singhal A. A study on cervical cancer screening in symptomatic women using Pap smear in a tertiary care hospital in rural area of Himachal Pradesh, India. Middle East Fertility Society Journal. 2017;22(1):39–42.

Mahadik JD, Patel S, Gupta S, Patel AS, Ramani PR. Epithelial abnormalities on Pap smear in Postmenopausal Women: A two-year hospital-based study. International Journal of Medical Science and Public Health. 2017;6(2):365–371.

Mehmetoglu HC, Sadikoglu G, Ozcakir A. Bilgel N. Pap smear screening in the primary health care setting: A study from Turkey. North American Journal of Medical Sciences. 2010;2(10):467–472.


No Supplementary Material available for this article.
Article Views      : 39
PDF Downloads : 16