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Karakteristik pasien dengan infeksi Burkholderia cepacia di RSUP Sanglah pada tahun 2014-2016


Background: Burkholderia cepacia complex (Bcc) is a group of 17 species that are genetically and phenotypically similiar. Bcc is an opportunistic pathogen in which it will cause an infection in a person who has had a previous severe lung infection or a person with a weak immune system.

Objective: This study aims to determine the characteristics of Burkholderia cepacia compleks patients at RSUP Sanglah Denpasar period 2014-2016 Sanglah Hospital.

Methods: This was an observational descriptive study with a cross-sectional study design and a retrospective approach. The subjects were 29 patients diagnosed with Burkholderia Cepacia bacteria and performed bacterial culture at Sanglah Hospital on January 1, 2014 s.d. December 31, 2016. The research data is secondary data obtained from the book Microbiology section Sanglah Hospital.

Results: The results showed that patients with isolated Burkholderia cepacia who were admitted to Sanglah Hospital consisted mostly of 37.9% old age categories (> 50 years) and adults (18-50 years); 65.5% male sex and 34.5% female gender; 62.1% were admitted to the ICU; 24.1% were diagnosed with sepsis;


  1. Acker Heleen, Sass Anrea, Bazzini Silvia, dkk. Biofilm-Grown Burkholderia Cepacia Complex Cell Seuvive Antibiotic Treatment by Avoiding Production of Reactive Oxygen Species. Plos One. 2013; 8(3)
  2. Gonzales Esther, Bakuoui Saesane, Gomes Margarida, dkk. A Functional oriT in the Ptw Plasmid of Burkholderia Cenocepacia Can Be Recognized by The R388Relaxase TrwC. Frontiers in Molecular Biosciences. 2016; 3(16)
  3. Gautam Vikas, Patil Prashant, Kumar Sunil, dkk. Multilocus Sequence Analysis reveals high genetic diversity in clinical isolates of Burkholderia Cepacia Compleks From India. Scientific Report; 2016.
  4. Attia Mohamed Ahmed Mahmoud. A Study on Burkholderia Cepacia in Susceptible Pharmaceutical Produts : Detection and Characteristic. Departement of Microbiology & Immunology Cairo University; 2016.
  5. Deng Peng, Wang Xiaoqiang, Baird Sonya, dkk. Comparative Genomw-wide analysis reveals that Burkholderia contaminant MS14 Possese Multiple Antimicrobial biosynthesis genes but not major genetic loci required for pathogenesis. Microbiology Open; 2016.
  6. Paul Liz, Hegde Ashwini, Pai Tanvi, dkk. An Outbreak of Bukholderia cepacia Bacteremia in a Neonatal Intensive Care Unit. Indian J Pediatr; 2016.
  7. Schweizer Katherine. Antibiotic Resistance in Burkholderia Species. Drug Resisitance Updares; 2016.
  8. Baldwind Adam, Mahenthiralingam Eshwar, Drevinek Pavel, dkk. Elucidating Global Epidemiology of Burkholderia Multivorans in Cases of Cystic Fibrosis by Multilocus Squence Typing. Journal of Clinical Microbiology. 2008;46(1):p.290-295
  9. Martinuci M, Rosceto E, Lula V.D, dkk. Accurate Identification of Members of Burkholderia Cepacia Complex in Cystic Fibrosis Sputum. Letters in Applied Microbiology; 2015.
  10. Lestari E.S &Severin J.A. Antimicrobial Resistance in Indonesia. Erasmus University Rotterdam; 2009.
  11. Omar Nancy, Raof Hala, Okasha Hadir, dkk. Microbiological Assesment of Burkholderia cepacia complex (Bcc) Isolates in Alexandria Main University Hospital. Alexandria Journal of Medicine. 2015;51:p.41-46
  12. Srinivasan Shoba, Arora Maj, Sahai Kavita. Report on the newly Emerging Nosocomial Burkholderia Cepacia in a Tertiary Hospital. Elsevier Medical Journal ARMED Forces India. 2016;70(6):p.4-8
  13. Jassem Agatha, Forbes Connor, Speert David. Investigation of Aminoglycoside Resistance Inducing Conditions and a Putative AmrAb-OprM Efflux System in Bukholderia Viatnemiensis. Annals of Clinical Microbiology and Antimicrobials. 2014;13(2)
  14. Bresler Adam, Kaye Keith, Lipuma John, dkk. Risk Factors for Burkholderia cepacia complex Bacteremia Among Intensive Care Unit Patients Withour Cystic Fibrosis : A Case Control Study. The Society for Healthcare Epidemiology of America; 2007.
  15. Righi E, Giradis M, Marchegiano P, dkk. Characteristics and Outcome Predictors of Patients Involved in an Outbreak of Burkholderia cepacia complex. Journal of Hospital Infection; 2013.
  16. Zlosnik James, Zhou Guohai, Brant Rollin, dkk. Burkholderia species infections in patients with cystic fibrosis in British Coluumbia, Canada. Annals of American Thoracic Society. 2014;12(1)
  17. Coburn Bryan, Wang Paulline, Caballero Diaz, dkk. Lung Microbiota Across Age and Disease Stage in Cystic Fibrosis. Scientific Reports; 2015.
  18. Kim Yeun Kyu, Yong Dongeun, Lee Kyungwon dkk. Burkholderia Sepsis as Hospital-Acquired Infection. Yonsei Medical Journal; 2016.

How to Cite

Antariksa, D., Budayanti, N. N. S., & Fatmawati, N. N. D. (2019). Karakteristik pasien dengan infeksi Burkholderia cepacia di RSUP Sanglah pada tahun 2014-2016. Intisari Sains Medis, 10(1).




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Dea Antariksa
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Ni Nyoman Sri Budayanti
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Ni Nengah Dwi Fatmawati
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