Research Article

Prevalensi gangguan tidur pada penderita parkinson di Poli Saraf RSUD Wangaya Denpasar tahun 2017

I Putu Gede Wikandikta , Dewa Putu Gde Purwa Samatra, Anak Agung Ayu Meidiary

I Putu Gede Wikandikta
Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Udayana. Email: wikandikta23@gmail.com

Dewa Putu Gde Purwa Samatra
Bagian/SMF Neurologi Fakultas Kedokteran Universitas Udayana, Rumah Sakit Umum Pusat Sanglah Denpasar-Bali

Anak Agung Ayu Meidiary
Bagian/SMF Neurologi Fakultas Kedokteran Universitas Udayana, Rumah Sakit Umum Pusat Sanglah Denpasar-Bali
Online First: December 01, 2020 | Cite this Article
Wikandikta, I., Samatra, D., Meidiary, A. 2020. Prevalensi gangguan tidur pada penderita parkinson di Poli Saraf RSUD Wangaya Denpasar tahun 2017. Intisari Sains Medis 11(3): 1085-1090. DOI:10.15562/ism.v11i3.232


Background: Parkinson's disease is one of the major causes of disability in the field of neurology and also the disease is chronic progressive. This disease is caused by the lack of dopamine levels in the body, especially the brain. Parkinson's disease affects a small part of the midbrain called susbstantia nigra. Parkinson's disease usually begins between the ages of 50 and 65, affecting about 1% of the entire population. Total cases of deaths from Parkinson's disease in Indonesia are ranked 12th in the world or 5th in Asia, with a prevalence of 1100 deaths in 2002.

Aim: This research aimed to know the prevalence of sleep disorders in patients with Parkinson Disease in Neurology Poly of RSUD Wangaya Denpasar.

Method: This research was a descriptive observational study with a cross-sectional approach. The subjects was 61 patients diagnosed with Parkinson Disease and did the treatment in Neurology Poly of RSUD Wangaya Denpasar from January 1, 2017, until December 31, 2017. This research is using primary data from the interview.

Results and Conclusion: Patients suffered Parkinson’s disease was 45.9% in 61 - 70 age group; 60.7% men; educational background of subjects was 62.3% senior high school; 36.1% private employee; 85.2% subjects had sleep disorders; 54.1% subjects had insomnia; ; 72.1% subjects didn’t have RLS;  82% subjects didn’t have EDS; 91.8% subjects didn’t have Nocturia.

 

Latar Belakang: Penyakit Parkinson adalah salah satu penyebab utama disabilitas di bidang neurologi dan juga penyakit ini bersifat kronik progresif. Penyakit ini disebabkan oleh kurangnya kadar dopamine dalam tubuh khususnya otak. Penyakit Parkinson memengaruhi bagian kecil dari otak tengah yang bernama susbstantia nigra. Penyakit Parkinson biasanya dimulai antara usia 50 dan 65, menyerang sekitar 1 % dari seluruh populasi. Total kasus kematian akibat penyakit Parkinson di Indonesia menempati peringkat ke-12 di dunia atau peringkat ke-5 di Asia, dengan prevalensi mencapai 1100 kematian pada tahun 2002.

Tujuan: Penelitian ini bertujuan mengetahui prevalensi munculnya gangguan tidur pada penderita Parkinson di Poli Saraf  Rumah Sakit Umum Daerah Wangaya Denpasar tahun 2017.

Metode: Penelitian ini merupakan penelitian deskriptif observasional dengan rancangan penelitian cross sectional. Subjek penelitian adalah 61 pasien yang terdiagnosis menderita Parkinson dan melakukan pengobatan di Poli Saraf RSUD Wangaya Denpasar pada rentang waktu 1 Januari 2017 s.d. 31 Desember 2017. Data penelitian adalah data primer yang diperoleh dari wawancara.

Hasil dan Kesimpulan: Pasien Parkinson terbanyak yaitu 45,9%  berusia 61-70 tahun; 60,7% berjenis kelamin laki-laki; 62,3% memiliki tingkat pendidikan SMA; 36,1% pegawai swasta; 85,2% mengalami gangguan tidur; 54,1% mengalami insomnia; 72,1% tidak mengalami RLS; 82% tidak mengalami EDS; 91,8% tidak mengalami nokturia.

References

DAFTAR PUSTAKA

Maass A, Reichmann H. Sleep and non-motor symptoms in Parkinson’s disease. Journal of Neural Transmission. 2013; 120(4):.565–569.

Neikrug AB et al. Effects of sleep disorders on the non-motor symptoms of Parkinson disease. Journal of clinical sleep medicine. JCSM. 2013; 9(11): 1119–29.

World Health Organization. Neurological disorders: a public health approach. Neurological disorders: public health challenges. 2006: 41–176.

Silitonga R. Faktor-faktor yang berhubungan dengan Kualitas Hidup Penderita PP di Poliklinik Saraf RS Dr Kariadi. (Thesis). Semarang. Program Pascasarjana Magister Ilmu Biomedik dan Program Pendidikan Dokter Spesialis I Ilmu Penyakit Saraf Universitas Diponegoro; 2007.

Okubadejo NU, Ojo OO, Oshinaike OO.. Clinical profile of parkinsonism and Parkinson's disease in Lagos, Southwestern Nigeria. BMC Neurology; 2010.

Karin W, Hans O.L, Philip C., Dimitrios, Jack M. Epidemiology and etiology of Parkinson’s disease: a review of the evidence. European Journal of Epidemiology. 2011; 26:1-58

Lees AJ, Hardy J, Ravest T. Parkinson’s Disease. Lanset. 2009; 373: 2055-2066.

Alatriste BV. et al. Prevalence and correlates of sleep disorders in Parkinson’s disease: a polysomnographic study. Arquivos de Neuro-Psiquiatria. 2015; 73(3): 241–245.

Braga NP, et al. Erratum: Snoring and excessive daytime sleepiness in Parkinson’s disease. Journal of the Neurological Sciences. 2004; 217: 41-45.

Tholfsen L. et al. Excessive daytime sleepiness in early Parkinson’s disease: a 5year follow-up. Sleep Medicine. Elsevier. 2004; 14: 19.

Knie B. et al. Excessive daytime sleepiness in patients with Parkinson’s Disease. 2011; 25: 203.

Ylikoski A, Martikainen K, Partinen, M. Parkinson’s Disease and Restless Legs Syndrome, European Neurology. 2015; 73(3): 212–219.

Bhalsing K. et al. Prevalence and profile of Restless Legs Syndrome in Parkinson’s disease and other neurodegenerative disorders: A case-control study. Elsevier Ltd. 2013; 19(4): 426–430.

Batla A, Veronique P, De Min, L. Nocturia in Parkinson’s Disease: Why Does It Occur and How to Manage?. Movement Disorders Clinical Practice. 2013; 3(5): 443–451.

Rana AQ, et al. Prevalence of nocturia in Parkinson’s disease patients from various ethnicities, Neurological research. 2013

Caap AM, Dehlin O. Insomnia and depressive symptoms in patients with Parkinson’s disease: Relationship to health-related quality of life. An interview study of patients living at home. Archives of Gerontology and Geriatrics. 2001; 32(1); 23–33.

Gjerstad, MD, et al. Insomnia in Parkinson’s disease: frequency and progression over time. Journal of Neurology, Neurosurgery & Amp. 2007; 78(5): 476 LP-479.

Zhu, K, Van HJJ, Marinus J. The course of insomnia in Parkinson’s diseas. Parkinsonism & Related Disorders. 2016; 33: 51–57.


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