Skip to main content Skip to main navigation menu Skip to site footer

Neuritis optik idiopatik dengan penyerta central serous chorioretinopathy sebagai manifestasi chronic relapsing inflammatory optic neuropathy: Sebuah laporan kasus

Abstract

Introduction: Idiopathic optic neuritis is an optic neuropathy with characteristics of optic nerve dysfunction that can be caused by various disorders of the optic nerve, including optic neuromyelitis, autoimmune optic neuropathy, chronic relapsing inflammatory optic neuropathy, myelin oligodendrocyte glycoprotein (MOG), idiopathic recurrent neuro retinitis, & optic neuropathy from systemic disease. This case report describes the occurrence of idiopathic optic neuritis that coexists with central serous chorioretinopathy (CSCR) as a possibility of chronic relapsing optic neuropathy.

Case description: A 39-year-old man with atypical optic neuritis due to idiopathic accompanied by CSCR in the right eye complained of sudden blurry vision with darkening of the lower visual field since 2 weeks & sudden worsening for 1 week prior to hospitalization. Eye examination showed visual acuity 1/300 in the right eye, grade III relative afferent pupillary defect (RAPD), round optic nerve head with blurred demarcation & undetermined cup disc ratio, and macular imaging examination showed CSCR. Perimetric examination revealed nonspecific. Idiopathic optic neuritis was treated with optic neuritis trial treatment for 4 days while CSC was observed. The results of the evaluation showed that visual acuity and CSC had improved. Idiopathic optic neuritis accompanied by the presence of CSCR can be managed & managed with a fairly good outcome.

Conclusion: In this case, the patient with atypical optic neuritis of idiopathic etiology accompanied by central serous chorioretinopathy in the right eye demonstrates a fairly favorable response to the administered corticosteroids.

 

Latar belakang: Neuritis optik idiopatik merupakan suatu neuropati optik dengan karakteristik disfungsi dari saraf optik yang dapat disebabkan oleh kumpulan berbagai kelainan pada saraf optik, diantaranya neuromyelitis optika, autoimmune optic neuropathy, chronic relapsing inflammatory optic neuropathy, myelin oligodendrocyte glycoprotein (MOG), idiopathic recurrent neuroretinitis, & neuropati optik dari penyakit sistemik. Laporan kasus ini memaparkan kejadian neuritis optik idiopatik yang muncul bersamaan dengan central serous chorioretinopathy (CSCR) sebagai kemungkinan sebuah chronic relapsing optic neuropathy.

Deskripsi kasus: Laki-laki usia 39 tahun dengan neuritis optik atipikal et causa idiopatik disertai dengan central serous chorioretinopathy pada mata kanan, mengeluhkan penglihatan buram mendadak disertai lapang pandangan menggelap pada bagian bawah sejak 2 minggu & memberat mendadak sejak 1 minggu sebelum ke rumah sakit. Pemeriksaan mata menunjukkan tajam penglihatan 1/300 pada mata kanan, relative afferent pupillary defect (RAPD) derajat III, papil nervus optikus bulat dengan batas kabur & cup disc ratio yang tidak dapat ditentukan, pemeriksaan pencitraan makula menunjukkan adanya CSCR, pemeriksaan perimetri didapatkan tidak spesifik. Neuritis optik idiopatik diterapi dengan optic neuritis trial treatment selama 4 hari, sedangkan CSCR dilakukan observasi. Hasil evaluasi didapatkan tajam penglihatan mengalami perbaikan & CSCR juga mengalami perbaikan. Neuritis optik idopatik yang disertai dengan adannya CSCR dapat diatasi & dikelola dengan hasil yang cukup baik.

Simpulan: Pasien neuritis optik atipikal et causa idiopatik disertai dengan central serous chorioretinopathy pada mata kanan dalam kasus ini menunjukkan respon yang cukup baik terhadap kortikosteroid yang diberikan.

References

  1. American Academy of Opthalmology. HIV Ocular Manifestation. AAOBCSC. 2019;5:334–5.
  2. Miller NR, Subramanian P, Patel V. Walsh & Hoyt’s Clinical Neuro-Ophthalmology: The Essentials [Internet]. Wolters Kluwer Health; 2016. Available from: https://books.google.co.id/books?id=VeZVCgAAQBAJ
  3. Soelberg K, Jarius S, Skejoe HPB, Engberg H, Mehlsen JJ, Nilsson AC, et al. A population-based prospective study of optic neuritis. Multiple Sclerosis Journal. 2017;23(14):1893–901. Available from: https://doi.org/10.1177/1352458517734070
  4. Fatima S, Triningrat AAMP, Kusumadjaja IMA, Budhiastra IP. Karakteristik Pasien Optic Neuritis di Rumah Sakit Umum Pusat (RSUP) Danglah Periode 1 Januari - 31 Desember 2018. Jurnal Medika Udayana . 2021;10(4):68–74.
  5. Chwalisz BK. Chronic relapsing inflammatory optic neuropathy (CRION). Vol. 80, Arquivos de Neuro-Psiquiatria. Associacao Arquivos de Neuro-Psiquiatria; 2022. p. 453–4.
  6. Cebeci Z, Oray M, Bayraktar Ş, Tuğal-Tutkun İ, Kır N. Atypical central serous chorioretinopathy. Turk Oftalmoloiji Dergisi. 2017;47(4):238–42.
  7. Khairallah M, Kahloun R, Tugal-Tutkun I. Central Serous Chorioretinopathy, Corticosteroids, and Uveitis. Ocul Immunol Inflamm. 2012;20(2):76–85. Available from: https://doi.org/10.3109/09273948.2011.650776
  8. Raimundo M, Fonseca C, Lemos J, Fonseca P. Central serous chorioretinopathy as a cause of vision loss in chronic relapsing inflammatory optic neuropathy. Am J Ophthalmol Case Rep. 2018;11:131–4.
  9. Petzold A, Plant GT. Chronic relapsing inflammatory optic neuropathy: a systematic review of 122 cases reported. J Neurol. 2014;261(1):17–26. Available from: https://doi.org/10.1007/s00415-013-6957-4
  10. Peng JT, Cong HR, Yan R, Kong XY, Jiang HQ, Wei W Bin, et al. Neurological outcome and predictive factors of idiopathic optic neuritis in China. J Neurol Sci. 2015;349(1–2):94–8.
  11. Molina-Carrión LE, Lira-Tecpa J, Jiménez-Arellano MP, Cruz-Domínguez MP, Medina G. Disease course of Chronic Relapsing Inflammatory Optic Neuropathy (CRION) in a single care center. Arq Neuropsiquiatr. 2022;80(5):510–5.
  12. Siuko M, Kivelä TT, Setälä K, Tienari PJ. The clinical spectrum and prognosis of idiopathic acute optic neuritis: A longitudinal study in Southern Finland. Mult Scler Relat Disord. 2019;35:215–20.
  13. Mary AM. Multiple Sclerosis. In: Netter’s neurology. 2nd ed. Philadelphia: Elsevier Saunders; 2012. p. 386–402.
  14. Lee HJ, Kim B, Waters P, Woodhall M, Irani S, Ahn S, et al. Chronic relapsing inflammatory optic neuropathy (CRION): A manifestation of myelin oligodendrocyte glycoprotein antibodies. J Neuroinflammation. 2018;15(1).

How to Cite

Paribrajaka, I. W. A., A.A. Mas Putrawati Triningrat, Made Paramita Wijayati, I Made Agus Kusumadjaja, & Ratnasari, L. M. N. . (2023). Neuritis optik idiopatik dengan penyerta central serous chorioretinopathy sebagai manifestasi chronic relapsing inflammatory optic neuropathy: Sebuah laporan kasus. Intisari Sains Medis, 15(1), 210–218. https://doi.org/10.15562/ism.v15i1.1947

HTML
0

Total
0

Share

Search Panel

I Wayan Ardy Paribrajaka
Google Scholar
Pubmed
ISM Journal


A.A. Mas Putrawati Triningrat
Google Scholar
Pubmed
ISM Journal


Made Paramita Wijayati
Google Scholar
Pubmed
ISM Journal


I Made Agus Kusumadjaja
Google Scholar
Pubmed
ISM Journal


Luh Made Novi Ratnasari
Google Scholar
Pubmed
ISM Journal