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Background: Some studies reported that measuring serum creatine kinase (CK) level is an objective method with which to determine the relative invasiveness of surgery. The purpose of this study was to evaluate the change in post-operative serum CK levels as a measure of whether the direct anterior approach (DAA) is less invasive than the posterior approach (PA) regarding postoperative rehabilitation.

Methods: This study design was a descriptive research with a qualitative approach, systematic literature review study. ResearchGate, Google Scholar and ScienceDirect searches reviewed changes in serum creatine kinase in patients after total hip arthroplasty. A total of 5 studies conducted between 2019-2023 were included in this review to present a literature review regarding changes in serum creatine kinase in patients after total hip arthroplasty.

Results: We analyzed biochemical markers of muscle damage in patients treated with total hip arthroplasty with minimally invasive and standard posterolateral approach to providing objective evidence of the local soft-tissue injury at the time of arthroplasty. A total of 42,890 titles were identified and 5 studies that met the requirements/criteria which discussed changes in serum creatine kinase in patients after total hip arthroplasty.

Conclusion: The objective measurement of muscle damage markers provides an unbiased way of determining the immediate effects of surgical intervention in patients treated with total hip arthroplasty.


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How to Cite

Dewabratha, B. (2023). Changes in creatine kinase serum in patient after total hip arthroplasty. Intisari Sains Medis, 14(3), 1222–1226.




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