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Gambaran klinis dan laboratoris penderita penyakit ginjal kronis yang menjalani hemodialisis di RSUD Muara Teweh, Barito Utara, Kalimantan Tengah

Abstract

Introduction: Chronic kidney disease (CKD) is defined by changes in kidney structure, function, or both. CKD shows a variety of clinical and laboratory abnormalities.

Purpose: This study aims to determine the clinical and laboratory features of CKD patients undergoing HD at Muara Teweh Hospital.

Methods: This research is an observational descriptive study conducted at the Hemodialysis Unit of Muara Teweh Hospital in January 2023. The sampling method used was total sampling.

Results: Most of the samples were female (56.1%), aged 40-60 years (68.3%), and had HD for more than 3 months (51.2%). The most common complaints were nausea (46.3%), muscle/bone pain (36.6%), and shortness of breath (34.1%). From the physical examination, it was found that most of them had grade II hypertension (48.8%), normal nutritional status (68.3%), oliguria (68.3%), and peripheral edema (63.4%). The average hemoglobin level was 9.05 g/dL, urea 128.80 mg/dL, and creatinine 9.17 mg/dL. The average glomerular filtration rate was 7.31 mL/min/1.73 m2.

Conclusion: The main clinical features of CKD in this study were nausea, muscle/bone pain, shortness of breath, grade II hypertension, normal nutritional status, and fluid retention while the laboratory features were anemia, uremia, and hypercreatininemia.

 

Pendahuluan: Penyakit ginjal kronis (PGK) merupakan kondisi kelainan medis yang ditandai dengan adanya  perubahan pada struktur ginjal, fungsi, atau keduanya. PGK menunjukkan beragam kelainan klinis dan laboratoris.

Tujuan: Penelitian ini bertujuan untuk mengetahui gambaran klinis dan laboratoris penderita PGK yang menjalani HD di RSUD Muara Teweh.

Metode: Penelitian ini merupakan penelitian deskriptif observasional yang dilakukan di Unit Hemodialisis RSUD Muara Teweh pada bulan Januari 2023. Metode pengambilan sampel yang digunakan adalah total sampling.

Hasil: Sebagian besar sampel berjenis kelamin perempuan (56,1%), berusia 40-60 tahun (68,3%), dan menjalani HD lebih dari 3 bulan (51,2%). Keluhan yang paling banyak ditemukan adalah mual (46,3%), nyeri otot/tulang (36,6%), dan sesak nafas (34,1%). Dari pemeriksaan fisik didapatkan sebagian besar mengalami hipertensi derajat II (48,8%), status gizi normal (68,3%), oliguria (68,3%), dan edema perifer (63,4%). Kadar rata-rata hemoglobin adalah 9,05 g/dL, ureum 128,80 mg/dL, dan kreatinin 9,17 mg/dL. Laju filtrasi glomerulus rata-rata adalah 7,31 mL/mnt/1,73 m2.

Simpulan: Gambaran klinis utama PGK pada penelitian ini adalah mual, nyeri otot/tulang, sesak nafas, hipertensi derajat II, status gizi normal, dan retensi cairan sedangkan gambaran laboratorisnya adalah anemia, uremia, dan hiperkreatininemia.

References

  1. Jager KJ, Kovesdy C, Langham R, et al. A Single number for advocacy and communication-worldwide more than 850 million individuals have kidney diseases. Kidney International. 2019; 96:1048-1050.
  2. GBD Mortality Causes of Death Collaborators. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015; 385:117-171
  3. Romagnani P, Levin A, Remuzzi G, Jager KJ. Chronic kidney disease. Nature Reviews Disease Primers. 2017; 3.17088.10.1038/nrdp.2017.88
  4. Riskesdas 2018. Hasil utama riset kesehatan dasar. Kementrian Kesehatan Republik Indonesia. 2018.
  5. Glassock, R.J., Warnock, D.G. & Delanaye, P. The global burden of chronic kidney disease: estimates, variability and pitfalls. Nature Reviews Nephrology. 2017; 13:104-114.
  6. Webster AC, Nagler EV, Morton RL, Masson P. Chronic kidney disease. Lancet. 2017; 389(10075):1238-1252.
  7. Vaidya SR, Aeddula NR. Chronic renal failure. StatPearls Publishing. 2022 Jan.
  8. Benghanem Gharbi, M. et al. Chronic kidney disease, hypertension, diabetes, and obesity in the adult population of Morocco: how to avoid "over"- and "under"-diagnosis of CKD. Kidney International. 2016; 89:1363-1371.
  9. Helal, I., Fick-Brosnahan, G.M., Reed-Gitomer, B. & Schrier, R.W. Glomerular hyperfiltration: definitions, mechanisms and clinical implications. Nature Reviews Nephrology. 2012; 8:293-300.
  10. Mehmood Y. Hemodialysis. Professional Medical Journal. 2019; 26(1):45-50.
  11. Aisara S, Azmi S, Yanni M. Gambaran klinis penderita penyakit ginjal kronik yang menjalani hemodialisis di RSUP Dr. M. Djamil Padang. Jurnal Kesehatan Andalas. 2018; 7(1):42-50.
  12. Pratiwi SN, Suryaningsih R. Gambaran klinis penderita penyakit ginjal kronik yang menjalani hemodialisis di RS PKU Muhammadiyah Surakarta. Proceeding Book Call for Paper Thalamus: Medical Research For Better Health. 2020; 427-439.
  13. Weinstein JR, Anderson S. The aging kidney: Physiological changes. NIH Public Access. 2010; 17(4):302-7.
  14. Rios E, Beca F. Uremic gastropathy. Dalam: Kireken HV. Encyclopedia of Pathology. 2014. Springer-Verlag Berlin Heidelbelrg; 1-3.
  15. Wang JS, Chiang, JH, Hsu HJ. lower risk of muskuloskeletal pain among patients with end stage renal disease treated by hemodialysis. Medicine. 2018; 97(3):1-7.
  16. Salerno FR, Parraga G, McIntyre CW. Why is your patient still short of breath? understanding the complex patophysiology of dyspnea in chronic kidney disease. Seminars in Dialysis. 2017; 30(1):50-57.
  17. Pawlaczyk W, Rogowski L, Kowalska J, et al. Assessment of the nutritional status and quality of life in chronic kidney disease and kidney transplant patients: a comparative analysis. Nutrients. 2022; 14:1-11.
  18. Daugirdas JT, Greene T, Rocco MV, et al. Effect of frequent hemodialysis on residual kidney function. Kidney International. 2013; 83:949-958.
  19. KDIGO Anemia Work Group. KDIGO clinical practice guideline for anemia in chronic kidney disease. Kidney International Supplements. 2012; 2:279–335.

How to Cite

Putra, I. G. S. S., & Islamiah, A. (2023). Gambaran klinis dan laboratoris penderita penyakit ginjal kronis yang menjalani hemodialisis di RSUD Muara Teweh, Barito Utara, Kalimantan Tengah. Intisari Sains Medis, 14(1), 538–542. https://doi.org/10.15562/ism.v14i1.1602

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I Gede Suprayoga Sukmana Putra
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Ahadini Islamiah
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