Review Article

Microstructural aspect of pineal body: pinealocytes population

Gede Wirata , Putu Nia Calista Santoso, Putu Ayu Utami Dewantari

Gede Wirata
Anatomy Department, Faculty of Medicine, Udayana University. Email: gede.wirata@unud.ac.id

Putu Nia Calista Santoso
Bachelor of Science Degree in Biology, Francisco J. Ayala School of Biological Sciences, University of California Irvine

Putu Ayu Utami Dewantari
Udayana University Hospital
Online First: January 25, 2018 | Cite this Article
Wirata, G., Santoso, P., Dewantari, P. 2018. Microstructural aspect of pineal body: pinealocytes population. Intisari Sains Medis 9(1). DOI:10.15562/ism.v9i1.151


Background: Pineal tissue was compound with 2 types of cell known as pinealocytes and astrocyte cell. Furthermore, microanatomical research of pineal body is a rare procedure conducted for several years even in Indonesia, and its anatomical aspect needs to be explained.  Aim: enrich the scope of knowledge related to mammalian pineal within the pineal body. Methods: 3 Wistar rats (Rattus novergicus), especially their pineal tissue, was extracted by pinealectomy method as a histotechnical procedure in a laboratory setting was prepared. Result: Pinealocytes characteristic are basophilic, large, regularly nucleus and a lot of mitochondria. On the other side, astrocyte has longer cytoplasmic processus found around the perivascular area and among the pinealocytes one. Conclusion: The quantities of pinealocytes appear as a most dominant cell that fills the inner part of the pineal body and probable to synchronize the production of melatonin and entirely supported by their neighbor, astrocyte cells.

 

Keywords: histotechnical method, pinealectomy, epiphysis

Keywords


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