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Pembesaran ginjal bilateral pada seorang anak dengan limfoma renal: sebuah laporan kasus

  • Listyani Gunawan ,
  • Pande Putu Yuli Anandasari ,
  • Ni Nyoman Margiani ,

Abstract

Background: Renal lymphoma is a tumor disorder that is rarely found in pediatrics, with only 0.7% cases of extranodal lymphoma from several previous studies. B cell non-Hodgkin lymphoma, including Burkitt lymphoma more common in pediatrics over 5 years old. Burkitt lymphoma is very aggressive in its development. This case report aims to evaluate bilateral renal enlargement in a child with renal lymphoma in radiology.

Case Presentation: In this case, it was reported that a 6 years old boy with complaints of a painless dilated stomach and weight loss since the last 2 months. Complaints that arise after a long period cause the mass development to be more diffuse and there has been infiltration, as well as pressure on the surrounding organs. Bilateral nephromegaly without lymph node enlargement or retroperitoneal mass on radiological images resembles bilateral nephroblastoma, but it points to Burkitt's lymphoma on histopathological examination. Radiological features may resemble other primary kidney tumors.

Conclusion: It is important to discuss the differential diagnosis of renal lymphoma; CT-Scan and MRI modalities are expected to be more specific in making the diagnosis and knowing the extent of the mass for consideration of the management that will be given. Early diagnosis and treatment improve prognosis to prevent and reduce patient morbidity and mortality.

 

Latar Belakang: Limfoma ginjal merupakan kelainan tumor yang sangat jarang dijumpai pada pediatrik, hanya 0.7% dari jumlah limfoma ekstranodal dari beberapa studi sebelumnya. Tipe Non-Hodgkin Lymphoma sel B termasuk di dalamnya Limfoma Burkitt, lebih sering dijumpai pada pediatrik berusia lebih dari 5 tahun. Limfoma Burkitt merupakan Non-Hodgkin Lymphoma sel B yang sangat agresif dalam perkembangannya. Laporan kasus ini bertujuan untuk mengevaluasi pembesaran ginjal bilateral pada seorang anak dengan limfoma renal secara radiologi.

Presentasi Kasus: Dalam kasus ini dilaporkan anak laki-laki berusia 6 tahun dengan keluhan perut yang semakin besar tanpa rasa nyeri dan penurunan berat badan sejak 2 bulan terakhir. Keluhan yang timbul setelah jangka waktu lama menyebabkan perkembangan massa semakin difus dan sudah terjadi infiltrasi, serta pendesakan terhadap organ di sekitarnya. Nefromegali bilateral tanpa disertai pembesaran kelenjar getah bening ataupun massa di retroperitoneal pada gambaran radiologi menyerupai nefroblastoma bilateral, namun pada pemeriksaan histopatologi mengarah kepada limfoma Burkitt. Gambaran radiologi dapat menyerupai tumor ginjal primer lainnya.

Simpulan: Penting untuk menyingkirkan diagnosa banding nefroblastomatosis dengan menggunakan modalitas pemeriksaan USG, CT-Scan maupun MRI. Diagnosa dan tatalaksana lebih dini meningkatkan prognosis, untuk mencegah dan mengurangi morbiditas dan mortalitas pasien.

Section

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How to Cite

Gunawan, L., Anandasari, P. P. Y., & Margiani, N. N. (2022). Pembesaran ginjal bilateral pada seorang anak dengan limfoma renal: sebuah laporan kasus. Intisari Sains Medis, 13(1), 1–5. https://doi.org/10.15562/ism.v13i1.1115

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Listyani Gunawan
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Pande Putu Yuli Anandasari
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Ni Nyoman Margiani
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